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You can also add food, containing alpha lipoic acid, to your diet. There have been studies performed by researchers in the past, detailing the benefits of alpha lipoic acid on treating people suffering from peripheral neuropathy.

Here are five incredible studies on how it can treat peripheral neuropathy:. The researchers discovered that alpha lipoic acid reduced nerve pain and had a positive influence on nerve conduction.

The study revealed that ALA could protect against nerve oxidative damage. They attributed ALA's quality in improving nerve pain and conduction to its antioxidant properties.

To come to this conclusion, the researchers tested the effects of alpha lipoic acid on 42 participants with diabetic neuropathy.

Patients who were treated with alpha lipoic acid showed a decrease in the ADMA levels. Increased ADMA levels have shown an increase in the symptoms of nerve pain in people with diabetes.

They also discovered that the paraoxonase and arylesterase levels in participants with diabetic neuropathy were higher than in participants not treated with alpha lipoic acid.

For this reason, ALA is one of the main ingredients that you will find in supplements for nerve pain. The researchers did conclude that more research into the beneficial properties of alpha lipoic acid needs to be performed but all the research that has been done up till now has shown it in the positive light of helping people with nerve pain.

The aim of the research was to examine the effects of alpha lipoic acid on patients with diabetes suffering from peripheral neuropathy. The researchers received a confirmation on ALA being used to treat nerve pain, concluding that it reduced the symptoms of nerve pain.

The researchers found out that the participants with nerve pain who were given a mg dose of alpha lipoic acid intravenously each day over three weeks displayed a significant improvement in the reduction of symptoms of nerve pain.

However, the researchers were unable to find out if people with nerve pain who were given supplements of alpha lipoic acid showed significant improvement in the reduction of symptoms of nerve pain.

To reach their conclusion, they used existing literature and studies. They examined the quality of each study using systematic reviews and standardized evaluation form used for RCTs.

Based on their results, the researchers stated that doctors should consider administrating alpha lipoic acid intravenously to people with diabetic neuropathy, as it can improve the symptoms in the short term, especially in people who do not respond to common neuropathy treatments.

They also said that more research on using ALA in treating nerve pain needs to be done. The researchers performed a clinical trial to examine the effects of alpha lipoic acid on diabetic participants suffering from neuropathic pain.

They performed a randomized, double-blind, and placebo-controlled trial with participants with diabetes participating in it. The study took place in two countries, Russia and Israel.

The researchers provided the participants with a mg, 1, mg, and 1, mg oral dose of alpha lipoic acid, giving it to them once a day for five weeks after giving them a placebo for one week.

The researchers noted seeing an improvement in the burning and stabbing pain experienced in peripheral neuropathy in the participants being treated with alpha lipoic acid.

At this point, ALA hasn't proven its effects on the human body. Recent studies have shown ALAs can regulate metabolism and inhibit the metabolism of fat in the liver.

Unfortunately, those findings are based on lab experiments involving cultured rat liver cells and skeletal muscles -- not bathing beauties [source: Treadwell ].

So, there's no indication the same results would occur in humans. One study conducted at the University of Ulsan College of Medicine in Seoul, Korea, found that ALA decreases the activity of fuel sensors in rats, causing the rodents to eat less and expend more energy, resulting in "profound" weight loss [source: National Center for Biotechnology Information ].

But until the same effect is observed in humans, there's probably no point in popping an ALA supplement to achieve weight loss. The bottom line is further research is necessary concerning ALA's effects on humans in regard to its use for weight loss.

In general, it's always best to use extreme caution when taking supplements. And if you do decide to incorporate ALA or any other supplement into your diet, be sure to share that information with your physician.

ALA synthesized by the body has only the R form. Cancer treatment chemicals can also cause it and HIV patients are prone to it [source: Mayo Clinic ].

More than 20 percent of diabetic patients develop peripheral neuropathy -- the leading cause of lower limb amputation. Oral and intravenous ALA is approved for use in Germany for treatment of diabetic neuropathy and in the U.

In a clinical trial, diabetic patients suffering from peripheral neuropathy who were given mg of ALA intravenously for 21 days reported a reduction in pain.

A larger study of diabetics with peripheral neuropathy who were injected with mg of ALA a day for three weeks, followed by 12 weeks of oral supplements, also experienced relief [source: Larsen ].

A small study in Austria found that more than half of the cancer patients who took ALA after getting the chemotherapy drug oxaliplatin reported an improvement in neuropathy symptoms [source: American Cancer Society ].

The National Cancer Institute is currently conducting a phase-3 study on ALA's use in preventing peripheral neuropathy in cancer patients undergoing chemotherapy treatment [source: Higdon , American Cancer Society ].

In , the FDA established new regulations to improve the consistency and safety of dietary supplements. Manufacturers are required to comply with the new standards by , including making sure the supplements don't contain contaminants or impurities and are properly labeled [source: American Cancer Society ].

Our bodies produce alpha lipoic acid and we can absorb it from a variety of foods including red meat and spinach. Alpha Lipoic Acid Benefits. Alpha Lipoic Acid Side Effects.

Alpha Lipoic Acid and Weight Loss. Alpha Lipoic Acid and Peripheral Neuropathy. Lots More Information. American Cancer Society.

While some small early studies produced promising results with the supplement, other data suggest that ALC does not work.

Other studies show that ALC helps control pain and may improve nerve function in people with neuropathy due to diabetes. B , B-6 , other B-complex vitamins may also ease symptoms of neuropathy.

B-complex vitamins play an essential role in nerve health, metabolism, and sensory perception. B-complex deficiencies are relatively common, and a person can develop a deficiency after just a few weeks of inadequate intake.

Alpha-lipoic acid ALA may help reverse free radical damage and intensify the effects of antioxidants , which may slow or stop nerve damage.

A handful of studies suggest that ALA may offer relief from some neuropathy symptoms, especially burning and stabbing pains, within a few weeks. A study evaluated symptoms of neuropathy after 5 weeks of taking oral doses of ALA once a day.

The researchers divided participants into three groups according to ALA dosages of milligrams mg , 1, mg, and 1, mg. Participants received a single oral dose of ALA each day, and researchers compared them with a placebo group.

At all three dosages, participants reported fewer symptoms. However, people who took higher doses experienced more side effects.

Another study found that people taking mg of alpha-lipoic acid along with mg irbesartan showed increased blood flow in the brachial artery, which is in the upper arm.

They also experienced lower levels of inflammation , suggesting the supplement may help with both blood flow and inflammatory processes.

The Foundation for Peripheral Neuropathy state that magnesium may help with chemotherapy-related neuropathy , but more research is needed.

A study published in Nutrients of people undergoing chemotherapy found that people who had high levels of magnesium in their diet were less likely to experience neuropathy.

An earlier study did not have the same outcome. Researchers found that giving magnesium and calcium infusions with chemotherapy did not improve neuropathy symptoms.

Magnesium is abundant in dark chocolate, nuts, avocados, and legumes. The Foundation for Peripheral Neuropathy also suggest that calcium could help with chemotherapy-related neuropathy, but again, research is limited.

However, the study published in Nutrients found that high dietary calcium had no effect on chemotherapy-induced neuropathy in some people.

It may improve many side effects of chemotherapy, including inflammation, muscle pain, and neuropathy. Several small studies have found that glutamine may eliminate or reduce the severity of neuropathy in people having chemotherapy.

However, researchers need to carry out further research to confirm these findings. Glutathione is an antioxidant that the body produces naturally.

It is an increasingly popular supplement, and some foods, such as okra , asparagus , and avocados , contain high levels of it. However, digestion breaks up glutathione, and the body does not absorb it , so people may need to use other methods.

Talk to a doctor about the best ways to take in glutathione. Preliminary research has found that glutathione may help with chemotherapy-related neuropathy, diabetic neuropathy , and neuropathy of unknown origin.

Not all studies have found that glutathione works, so more research must assess its role in nerve health.

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Here are five incredible studies on how it can treat peripheral neuropathy:. The researchers discovered that alpha lipoic acid reduced nerve pain and had a positive influence on nerve conduction.

The study revealed that ALA could protect against nerve oxidative damage. They attributed ALA's quality in improving nerve pain and conduction to its antioxidant properties.

To come to this conclusion, the researchers tested the effects of alpha lipoic acid on 42 participants with diabetic neuropathy.

Patients who were treated with alpha lipoic acid showed a decrease in the ADMA levels. Increased ADMA levels have shown an increase in the symptoms of nerve pain in people with diabetes.

They also discovered that the paraoxonase and arylesterase levels in participants with diabetic neuropathy were higher than in participants not treated with alpha lipoic acid.

For this reason, ALA is one of the main ingredients that you will find in supplements for nerve pain. The researchers did conclude that more research into the beneficial properties of alpha lipoic acid needs to be performed but all the research that has been done up till now has shown it in the positive light of helping people with nerve pain.

The aim of the research was to examine the effects of alpha lipoic acid on patients with diabetes suffering from peripheral neuropathy.

The researchers received a confirmation on ALA being used to treat nerve pain, concluding that it reduced the symptoms of nerve pain.

The researchers found out that the participants with nerve pain who were given a mg dose of alpha lipoic acid intravenously each day over three weeks displayed a significant improvement in the reduction of symptoms of nerve pain.

However, the researchers were unable to find out if people with nerve pain who were given supplements of alpha lipoic acid showed significant improvement in the reduction of symptoms of nerve pain.

To reach their conclusion, they used existing literature and studies. They examined the quality of each study using systematic reviews and standardized evaluation form used for RCTs.

Based on their results, the researchers stated that doctors should consider administrating alpha lipoic acid intravenously to people with diabetic neuropathy, as it can improve the symptoms in the short term, especially in people who do not respond to common neuropathy treatments.

They also said that more research on using ALA in treating nerve pain needs to be done. The researchers performed a clinical trial to examine the effects of alpha lipoic acid on diabetic participants suffering from neuropathic pain.

They performed a randomized, double-blind, and placebo-controlled trial with participants with diabetes participating in it. The study took place in two countries, Russia and Israel.

The researchers provided the participants with a mg, 1, mg, and 1, mg oral dose of alpha lipoic acid, giving it to them once a day for five weeks after giving them a placebo for one week.

The researchers noted seeing an improvement in the burning and stabbing pain experienced in peripheral neuropathy in the participants being treated with alpha lipoic acid.

However, people who were given an increased dose of alpha lipoic acid exhibited symptoms such as vertigo, vomiting, and nausea.

At the end of the study, the researchers concluded that oral treatment of alpha lipoic acid given for 5 weeks could improve symptoms of nerve pain in people suffering from diabetes.

There are also reports that ALA may have health benefits in relation to cataracts, seizures, kidney damage and liver disease, but additional studies are necessary before any definite conclusion is drawn.

In addition, ALA, like just about any other medication or supplement, is not without its side effects. Read on to find out more about ALA's side effects.

Scientists first discovered the ALA compound in bacteria back in At one time scientists believed ALA was a vitamin -- substances the body needs, but can't produce on its own.

But in , it was identified as an antioxidant crucial to energy production in the body [source: American Cancer Society ]. However, the jury is still out on the long-term effects of taking ALA supplements.

Anyone with pre-existing medical conditions should exercise caution. Children are not advised to take ALA. Pregnant and nursing women should consult their doctors before taking it.

Diabetics who take ALA must monitor their blood sugar levels carefully, because the supplements may lower blood glucose levels [source: National Center for Complimentary and Alternative Medicine ].

ALA may also lower levels of thyroid hormone and thyroid-regulating medications Levothyroxine. Hormone levels should be monitored closely for those taking thyroid hormones and ALA supplements [source: University of Maryland Medical Center ].

There is also concern that ALA might interfere with radiation therapy or chemotherapy by making the treatments less effective [source: American Cancer Society ].

Unlike prescription drugs, supplements like ALA capsules don't have to be approved by the FDA before they are released on the market.

Nor are they tested for their adverse affects when taken with other medication. In , supplements accounted for almost 24, calls to U. That's why it's always best to check with your doctor before taking any herbal remedy.

It takes a variety of antioxidants to protect a cell from free radicals. ALA may be able to convert other antioxidants to their active forms, namely vitamins C and E, Coenzyme Q10 and glutathione [source: Treadwell ].

But if you're a human looking to slim down for bikini season, you should probably stick with your diet and exercise plan. At this point, ALA hasn't proven its effects on the human body.

Recent studies have shown ALAs can regulate metabolism and inhibit the metabolism of fat in the liver. Unfortunately, those findings are based on lab experiments involving cultured rat liver cells and skeletal muscles -- not bathing beauties [source: Treadwell ].

So, there's no indication the same results would occur in humans. One study conducted at the University of Ulsan College of Medicine in Seoul, Korea, found that ALA decreases the activity of fuel sensors in rats, causing the rodents to eat less and expend more energy, resulting in "profound" weight loss [source: National Center for Biotechnology Information ].

Neuropathy is nerve damage that often occurs in people with diabetes and as a side effect of chemotherapy. Although lifestyle changes and conventional treatments may ease symptoms of neuropathy, supplements may also help.

Symptoms of peripheral neuropathy include:. Treatment for neuropathy usually involves managing the condition that has caused it and relieving symptoms.

Research into using supplements and natural remedies for neuropathy is ongoing. Supplements may have fewer side effects than conventional treatments and have other health benefits.

As with any medication, anyone wanting to try supplements should discuss the risks and benefits with a doctor first. Anyone experiencing severe side effects should seek medical advice as soon as possible.

In this article, we examine vitamin and supplements that may help reduce symptoms of neuropathy, prevent it from occurring, or even reverse nerve damage.

We also discuss dietary and lifestyle tips for neuropathy and look at when to seek advice from a doctor. Acetyl-l-carnitine ALC is a popular supplement for treating a wide variety of symptoms.

The liver and kidneys naturally produce it. People undergoing chemotherapy may find relief from neuropathy with ALC. However, the data supporting its use are mixed.

While some small early studies produced promising results with the supplement, other data suggest that ALC does not work.

Other studies show that ALC helps control pain and may improve nerve function in people with neuropathy due to diabetes.

B , B-6 , other B-complex vitamins may also ease symptoms of neuropathy. B-complex vitamins play an essential role in nerve health, metabolism, and sensory perception.

B-complex deficiencies are relatively common, and a person can develop a deficiency after just a few weeks of inadequate intake.

Alpha-lipoic acid ALA may help reverse free radical damage and intensify the effects of antioxidants , which may slow or stop nerve damage.

A handful of studies suggest that ALA may offer relief from some neuropathy symptoms, especially burning and stabbing pains, within a few weeks.

A study evaluated symptoms of neuropathy after 5 weeks of taking oral doses of ALA once a day. The researchers divided participants into three groups according to ALA dosages of milligrams mg , 1, mg, and 1, mg.

Participants received a single oral dose of ALA each day, and researchers compared them with a placebo group.

At all three dosages, participants reported fewer symptoms. However, people who took higher doses experienced more side effects. Another study found that people taking mg of alpha-lipoic acid along with mg irbesartan showed increased blood flow in the brachial artery, which is in the upper arm.

They also experienced lower levels of inflammation , suggesting the supplement may help with both blood flow and inflammatory processes.

The Foundation for Peripheral Neuropathy state that magnesium may help with chemotherapy-related neuropathy , but more research is needed.

A study published in Nutrients of people undergoing chemotherapy found that people who had high levels of magnesium in their diet were less likely to experience neuropathy.

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